10 Best Sinus Medicines

Updated December 2024

Top Choice

Tylenol Sinus + Headache Non-Drowsy Daytime Caplets with Acetaminophen & Phenylephrine HCl, 24

9.8

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Advil Sinus Congestion And Pain Relief, 200mg Ibuprofen, Pain and Fever Reducer,

Advil Respiratory

9.4

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Vicks Sinex Severe Sinus Pressure, Pain, Congestion, and Headache Relief, 24 LiquiCaps (Non-Drowsy)

9.3

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Boiron Sinusalia Sinus Relief, 60 Tablets

8.8

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Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Tablets, 20 ct

8.5

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Alka-Seltzer Plus Severe Sinus, Cold & Cough Liquid Gels 20ct

ALKA-SELTZER PLUS

8.4

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Equate Severe Allergy and Sinus Headache 20 Caplets (Pack of 2)

Equate Severe Allergy and Sinus Headache 20 Caplets (Pack of 2)

8.1

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Advil Sinus Congestion & Pain Relief (50 Count Packets), Non-Drowsy, 200mg Ibuprofen Pain

Advil Respiratory

7.7

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Rite Aid Sinus & Allergy Relief PE Tablets, Maximum Strength - 24 Count

7.5

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Nature's Way Umcka Allergy and Sinus Homeopathic Chewable Tablets- Cherry Flavor- 20 Count

7.1

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